At a Glance
The Red Devils' poor run of form continued at Leeds' fortress, but head coach Ruben Amorim had Matheus Cunha to thank for his side not suffering even more damage against their old rivals.
The Everton loanee directed a first-period effort against the post for the confident hosts before the American midfielder applied a cool finish with a driven, 62nd-minute shot.
With the goal, Amorim was under intense scrutiny after his side had been held by struggling Wolverhampton Wanderers at Old Trafford earlier in the week.
However, against opponents who had less time to recover, the forward restored parity three minutes after the opener when he latched onto a pass from introduced Joshua Zirkzee and guided a shot underneath advancing Leeds goalkeeper Lucas Perri.
It was only the Brazilian's fourth Premier League goal since his big-money summer move and came at a time when the manager is without several key attacking players due to a mix of injury and international duty.
Not that you would expect the hosts to sympathise with that given their own tight schedule.
The Swiss attacker forced a full length save out of visiting goalkeeper Senne Lammens with a audacious overhead kick, and United heads were in hands when the Slovenian striker, who is struggling to make an impression, turned his teammate's cut-back wide from close range.
The goalscorer, who had a goal disallowed for offside much earlier in the contest, also blasted against a post in the dying moments.
The draw prolongs Leeds' unbeaten run to seven games, their longest such streak since 2001, and takes them eight points clear of the drop zone.
For the visitors though, it was yet another opportunity to move into fourth spot, albeit only for a matter of hours, wasted.
With the AFCON reaching its knockout phase, the United coach could be forgiven for hoping the involved countries make a swift exit.
Current injuries to captain Bruno Fernandes and Three Lions star Mason Mount only heightened the impact the absence of other attackers is having on the team's options.
It's not that the absent players are the solution to all of United's problems. After all, they were part of the side that experienced disappointing results earlier in the season.
But without them, the boss has few alternatives in attack.
He evidently does not trust teenager Shea Lacey or the seasoned Joshua Zirkzee, even though the Dutch forward provided the assist for Cunha's equaliser almost immediately after his introduction as a substitute.
That leaves Cunha, who has now scored a small tally in five games, and others playing out of their preferred positions, alongside Sesko.
On this evidence, the expensive frontman looks no better than previous underwhelming signings, lacking in confidence and assurance in front of goal.
His failure to turn home Zirkzee's cross means it is now a long run without a goal for the new signing.
After thrilling victories in their previous home games, the arrival of their fiercest rivals to home was a bit drab affair.
True, there were moments of typical atmosphere, but the hostile edge was not as pronounced as in other encounters.
The home fans were more concerned about their side's struggle to get worthwhile possession in advanced areas for any prolonged period.
The striker's header that clipped the post was an isolated moment of threat in a congested first half.
It still felt as though Leeds were struggling when a defensive error opened the door for the opener.
Ever so briefly, Leeds' delirious fans thought they were about to secure a rare win against their old foes.
However, there is a much bigger picture for the manager and the club to deal with.
When they endured a difficult run of form earlier in the campaign, many speculated about the manager's position.
Instead, he is now overseeing clear improvement.
The job is not done yet but gradually, the team are getting nearer to securing their survival.
The Yorkshire club have a top-flight trip to St James' Park in midweek, followed by the start of their domestic cup campaign next weekend. The Red Devils face a Premier League trip to Turf Moor before also beginning their cup journey with a home tie.
Elena is a tax policy analyst with over a decade of experience in interpreting IRS data and advocating for taxpayer rights.